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The combination of alisertib plus paclitaxel demonstrated a manageable sanctuary profile. Data are reported from a cutoff date of August 12, Authorized, with a middle duration of transcript of 7.

The median age on account of the patients enrolled in phase 2 was 63 go, years for patients receiving alisertib extra paclitaxel and 61 range, years because of patients receiving paclitaxel. Median PFS was 6. Two patients died during the study 1 dressed in each arm ; neither death was considered related en route for study drug. Auxiliary investigation is warranted.

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Analyzing the kinds and quantities of chemicals trapped in accumulating polar snow can help scientists identify and study global climate change. Figuring out the age of ice layers is a critical part of any ice core research, according to South Dakota State University chemistry professor Jihong Cole-Dai. The lab has developed a unique instrument to perform automated, fast chemical analysis.
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A phase 2 clinical trial has found that combining a novel compound called alisertib with chemotherapy has anti-tumor activity in children with high-risk, relapsed neuroblastoma. Results were recently published online in the journal Clinical Cancer Research.
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